A New Class Of Suppressive T Cells Promotes Self Recognition and Prevents Autoimmunity, Plus a Warning
This story on regulatory T cell function and its therapeutic potential falls within a greater series on regenerative medicine. In 1999, I defined regenerative medicine as the collection of interventions that restore to normal function tissues and organs that have been damaged …
CAR T Therapy May Cause Rare Cancer & How CRISPR Could Be The Solution
Could CAR T Therapy, an innovative treatment for certain blood cancers, cause lymphoma? Reports from clinical trials and data released after product approval suggest that the treatment could trigger the development of cancerous T cells in rare cases. Although the therapy’s benefits …
Viral Awakening: The Hidden Threat of Human Herpes 6 (HHV-6) in CAR T Therapy
Before any treatment, each clinician and patient must determine whether the anticipated benefits outweigh the potential toll caused on the body. Study results published in Nature suggest that latent virus reactivation may be a valid point to consider for CAR T and …
Addressing global health and regulations at the USP Convention
Dr Krishna Reddy was invited to the South Asia Chapter Meeting of the US Pharmacopeia Convention held in New Delhi on November 15. The convention aimed to discuss the evolving regulatory landscape, building resilient API supply chains and access to affordable biosimilars. …
ACCESS Health International signs SACH pledge for a sustainable future
ACCESS Health International has taken a step towards a sustainable and healthier future by signing the Sustainable Action for Climate and Health Initiative (SACH) pledge organized by the United States Agency for International Development (USAID), PATH and Centre for Health Research and …
ACCESS Health India showcases vision for integrated healthcare delivery at Christian Medical College Medicine Annual Conference
ACCESS Health India participated in the 2023 Christian Medical College Vellore Annual Conference (MAC), on November 23 and 24. The conference brings together industry professionals to explore clinical approaches to addressing health disparities and strengthening primary and secondary-level healthcare. ACCESS Health India hosted …
Seeking a Solution: Probiotic-Guided CAR T Cells for Solid Tumors
Beyond yogurt ads and health supplements, probiotics could revitalize cell-based cancer immunotherapies such as CAR T therapy. Surprisingly, a paper published in Science demonstrates show how these live microorganisms can guide supercharged T cells into the solid tumor environment—a feat that current …
UK Approves Groundbreaking CRISPR-based Gene Therapy for Sickle Cell Disease and Thalassemia
This week marks an incredible win for modern medicine. The first CRISPR-based gene therapy has just been approved for clinical use in the United Kingdom. Casegvy (Exa-cel), developed by Vertex and CRISPR Therapeutics, relies on a precise gene-cutting technology first published in …
Opening the Floodgates: The Role of SRC-3 in Regulatory T Cell Suppression
Opening the floodgates of the immune system could help the body fight cancer. As described in a previous installment, researchers at the Baylor College of Medicine successfully eliminated breast and prostate tumors in mice by altering the expression of a specific protein …
How Regulatory T Cells Can Reduce Solid Tumors in Mice
This is the first installment in a group of stories on regulatory T cell function and its potential to treat cancer. This work falls within a greater series on regenerative medicine. In 1999, I defined regenerative medicine as the collection of interventions …
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