Hepatitis-C Drugs And A Remdesivir Metabolite As New Anti-Covid-19 Drugs: The Viral Protein NSP3 Emerges As A New Target.
In the search for new ways to use small molecule drugs to prevent and treat Covid-19 infections, a surprising synergy has emerged. Two drugs—Remdesivir metabolite GS-441524 and combination Hepatitis-C antivirals—both of which target NSP3 hold immediate promise for prevention and treatment of …
Pediatric Mental Health Is In Crisis
A syndemic refers to multiple interrelated epidemics happening at the same time. Covid-19 has unleashed and amplified a number of simultaneous personal, social, medical, political, and economic crises. This article is part three of a series of articles exploring the impact of …
Don’t Let Children Be The Casualties Of Covid-19 Complacency
Collecting comprehensive data on how children are affected by Covid-19 has been neglected in favor of competing priorities during the pandemic. Yet as overall cases currently decline in the U.S., an increasing percentage of cases are children, the issue demands urgent attention. …
Can We End the Pandemic?
The emergence of dangerous new coronavirus variants is threatening the progress that we have made with the help of COVID-19 vaccines. It is now clear that our pharmaceutical research efforts and public-health interventions will need to be redoubled – and without any …
New Drug May Bypass SARS-CoV-2 Blockade Of Innate Immune Response
Scientists have identified a small molecule drug that might prevent and treat Covid-19 by targeting a cellular gene that bypasses SARS-CoV-2 blockade of the innate immune response. The drug, diABZI, is currently undergoing phase II clinical trials as a potential cancer treatment. …
United Kingdom Data Show Population Based Rapid Antigen Tests Are A Potent Covid Control Tool
Of the many different strategies countries are adopting to combat Covid-19, an increasing number include rapid antigen testing. Austria recently committed to the purchase of rapid tests, while in Canada a program was launched that aims to distribute rapid tests for workplace …
The Premonition By Michael Lewis Highlights A Longstanding Need For Structural Reform Of The US Public Health Service
In the face of horrific death tolls and unspeakable trauma, there has been a continued refrain of “never again” through the pandemic. We want the small comfort of knowing that the deaths have not been entirely in vain. Yet history demonstrates that …
Discovery Of A Novel Monoclonal Antibody That Neutralizes A Broad Range Of Coronaviruses
The Covid-19 pandemic is no isolated incident. Coronaviruses have been coming after us for years. In the past 60 years, there have been as many as five seasonal cold-causing coronaviruses. In the past 20 years, we have dealt with three lethal coronaviruses: …
Making The Best Of A Tough Situation: How To Respond To The CDC’s New Mask Guidance
The confusion caused by the Centers for Disease Control when it issued new masking guidance for those vaccinated has already been well debated. The CDC claims that vaccinated people can remove their masks indoors and out, since they pose little risk of …
A New Twist To Antibody Cocktails To Prevent And Treat Covid-19
Monoclonal antibodies have proved effective in the prevention and treatment of Covid-19. Their effectiveness depends on the recognition of specific structures on the surface of the viral spike protein. Over the past six months, we have learned that many of these shape-specific …
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