Can Artificial Intelligence Help Eliminate Health Disparities?
Artificial intelligence (AI) has quickly become one of the most promising new tools in healthcare. Not only has it been used to improve individual health outcomes by streamlining diagnosis and treatment, but recent studies have begun to explore its ability to improve …
Gene Therapy for a Neurological Disease: Rett Syndrome
Gene therapy may offer hope for people with a rare childhood disease called Rett syndrome. Around one in 10,000 girls are born each year with Rett syndrome, a rare genetic condition that impacts brain development. People with Rett syndrome grow without issue …
Direct Administration of CRISPR-Cas9: Tools for Cell and Gene Therapy
Newly published research offers a novel technique to address a classic problem. Several of the latest cell-based gene and cancer therapies suffer similar drawbacks. The first is that cell manipulation occurs outside the body, a lengthy process that requires extracting, purifying, and …
Artificial Intelligence to Manage the AMD Burden
By 2040, 288 million people worldwide are projected to have age-related macular degeneration (AMD).1 The increasing number of AMD cases calls for more frequent eye examinations. As a result, ophthalmologists will need more time to analyze patient data due to the heavier …
Sniffing Female Tears Reduces Male Aggression
KEY POINTS Tears emit a social chemical signal that is picked up by the olfactory system and lowers aggression in males. Chemical signals in tears strengthen the connection between the aggression and olfactory parts of the brain. This study suggests that tears …
Can CAR T Therapy Be Delivered By Direct Injection?
What if CAR T cells, revolutionary cancer fighters normally manufactured in the lab, could be created inside the patient? This quest to simplify CAR T therapy has brought two biotech companies to a similar answer: viral injections. According to research presented at …
Progress in Treating High Cholesterol: Clinical Trial Interim Results
A new, CRISPR-powered gene therapy seeks to rewrite the rules of cholesterol care. The treatment promises to obliterate ‘bad’ cholesterol with a single infusion, marking a potential paradigm shift in cardiovascular care. A Gene for Bad Cholesterol The balance between “good” cholesterol …
Cre-LoxP: Issues Modulating Genes in the Immune System
Cancer and other diseases could be treated by turning certain genes on and off in the immune system. The method used to activate and inactivate these genes is critical to consider. If the technique does not pinpoint the right cells or lingers …
A New Class Of Suppressive T Cells Promotes Self Recognition and Prevents Autoimmunity, Plus a Warning
This story on regulatory T cell function and its therapeutic potential falls within a greater series on regenerative medicine. In 1999, I defined regenerative medicine as the collection of interventions that restore to normal function tissues and organs that have been damaged …
CAR T Therapy May Cause Rare Cancer & How CRISPR Could Be The Solution
Could CAR T Therapy, an innovative treatment for certain blood cancers, cause lymphoma? Reports from clinical trials and data released after product approval suggest that the treatment could trigger the development of cancerous T cells in rare cases. Although the therapy’s benefits …
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