Progress In Tissue Engineering: Controlling Cell-Cell Signaling
Cells are the fundamental unit of life. The average human body contains around 30 trillion cells with varying functions and potentials. Communication between cells is central to the body’s ability to form tissues and organs, and to coordinate critical functions throughout the …
You Can Now Control A Wheelchair With Your Brain Waves Alone
Scientists at the University of Padova in Italy have proven that by using a completely non-invasive brain-machine interface technology, those who are fully paralyzed can drive a wheelchair simply by using their minds and a cap that decodes their brain waves. Brain-machine …
Synthetic Gene Circuit To Hone CAR T Therapy
Here we describe a new way to control CAR T therapy through synthetic gene circuits. For more on controlling CAR T therapy, read our article on the use of antibody switches to control CAR T cell activation. Previous installments also discuss the fundamentals …
CAR T Therapy, A Promising New Therapy For Multiple Sclerosis?
Here we describe the use of CAR T therapy to treat multiple sclerosis in mice. Previous installments discuss the fundamentals of CAR T and its applications for B cell cancers, multiple myeloma, lupus, rheumatoid arthritis and the heart, as well as use of antibody switches to control …
CAR T Therapy To Treat And Cure Rheumatoid Arthritis
Here we describe the use of CAR T therapy to treat mice with experimental rheumatoid arthritis. Previous installments discuss the fundamentals of CAR T and its applications for B cell cancers, multiple myeloma, lupus and the heart, as well as the use of antibody switches to control …
Reimagining Alzheimer’s (Part 7): Cholesterol Abnormalities May Contribute To Alzheimer’s Disease
This article is the seventh installment in my series on Alzheimer’s disease. Read more about Alzheimer’s disease in part 1, part 2, part 3, part 4 , part 5, and part 6 of the series. An Introduction to APOE4 A recent study published in Nature provides new insights into genetic predispositions to …
The Fat Truth: You Feel It In Your Gut
With thanksgiving in the rear-view window, the last thing most of us want to do is think about food, not to mention what those calories did to our waistlines. From deep-fried turkey to loaded mashed potatoes to freshly baked apple pie, there …
Teaming Up Two Biotech Winners to Fight Cancer: CRISPR and CAR T
Here we describe early clinical trial results on combination CRISPR and CAR T therapy, a sequel to an earlier, introductory piece. Other alternative CAR T designs include mRNA vectors to create temporary CAR T cells and the use of antibody switches to …
Reimagining Alzheimer’s (Part 6): The Many Effects Of The APOE4 Variant
This article is the sixth installment in my series on Alzheimer’s disease. Read more about Alzheimer’s disease in part 1, part 2, part 3, part 4 , and part 5 of the series. A recent paper published in the journal Nature has revealed a new mechanism by which …
CRISPR Technology To Simplify And Enhance CAR T Cancer Treatment
Here we describe the integration of CRISPR gene-editing technology to improve CAR T therapy design. Other alternative CAR T designs include mRNA vectors to create temporary CAR T cells and the use of antibody switches to control CAR T cell activation. Previous installments discuss the fundamentals …
Recent Comments